Top supplements for colitis
Certain supplements can help reduce inflammation and support gut health. Probiotics help restore beneficial gut bacteria and improve digestion. Omega-3 fatty acids from fish oil may help reduce inflammation in the intestines. Turmeric (curcumin) has anti-inflammatory properties that may assist in maintaining remission. L-Glutamine supports gut healing and reduces irritation.

1
Digestive Enzymes
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People with colitis often struggle with digestion and nutrient absorption. Digestive enzyme supplements can help break down food more effectively and reduce bloating and discomfort.

2
L-Glutamine
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An essential amino acid that supports gut lining repair and helps prevent leaky gut. It may reduce diarrhea and inflammation while supporting overall intestinal health.

3
Psyllium Husk (Soluble Fiber)
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If tolerated, psyllium husk helps regulate bowel movements by adding bulk to stools. It can help manage diarrhea or constipation, but some people with colitis may need to avoid excessive fiber during flare-ups.

4
Slippery Elm
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This plant-based supplement forms a soothing mucilage in the intestines, helping to reduce inflammation and protect the gut lining from irritation. It can ease symptoms like diarrhea and abdominal discomfort.

5
Probiotics
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Beneficial bacteria like Lactobacillus and Bifidobacterium help restore gut flora, improve digestion, and reduce inflammation. Probiotics can help maintain remission in colitis and reduce symptoms like bloating and diarrhea.

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Collagen Peptides
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Collagen supports gut lining integrity and helps heal damage caused by inflammation. It contains amino acids like glycine and proline, which promote intestinal health.

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Resveratrol
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Found in grapes and berries, resveratrol is a natural anti-inflammatory compound that may help regulate immune response and gut inflammation in colitis patients.

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Methylated B Vitamins (B12, B6, Folate)
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Colitis can cause B-vitamin deficiencies due to malabsorption. Methylated forms of B12 (methylcobalamin) and folate are easier to absorb and help support energy, brain function, and gut health.

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Magnesium
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Many people with colitis experience magnesium deficiency due to malabsorption. Magnesium supports digestion, prevents muscle cramping, and helps regulate bowel movements. Magnesium glycinate or citrate is best for absorption.

10
Turmeric (Curcumin)
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Curcumin, the active ingredient in turmeric, has powerful anti-inflammatory effects and has been shown to reduce colitis symptoms and maintain remission when taken consistently. Look for bioavailable curcumin supplements (with black pepper extract).

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Vitamin D
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Many colitis patients have low vitamin D levels, which can increase inflammation and affect immune function. Taking 1,000–5,000 IU daily may help reduce disease severity and improve gut lining integrity.

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Chamomile Extract
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Chamomile has natural anti-inflammatory and calming effects, making it beneficial for soothing an irritated digestive system and reducing stress-related flare-ups.

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Zinc
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Zinc is essential for immune function and gut repair. Since chronic inflammation can lead to zinc deficiency, supplementing may help with gut healing and reducing colitis symptoms.

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Boswellia Serrata
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This herbal extract has potent anti-inflammatory effects similar to NSAIDs but without the gut irritation. It can help reduce colitis flare-ups and support gut healing.

15
Quercetin
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A plant-based flavonoid with anti-inflammatory and antioxidant properties that may help reduce intestinal inflammation and oxidative stress in colitis patients.

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Aloe Vera Gel Capsules
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Aloe vera has natural soothing and anti-inflammatory properties, helping to heal the gut lining and reduce irritation in the intestines. It can be beneficial for mild-to-moderate colitis.

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Omega-3 Fatty Acids (Fish Oil, Flaxseed Oil)
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Omega-3s have anti-inflammatory properties that help reduce intestinal inflammation. Found in fish oil or flaxseed, they can lower flare-up frequency and promote gut healing.

18
N-Acetyl Glucosamine (NAG)
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Helps support mucosal repair and gut lining health, potentially reducing colitis symptoms by strengthening the intestinal barrier.