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Here are the most common gluten intolerance symptoms.

Gluten intolerance symptoms can vary in severity among individuals. Gluten intolerance symptoms vary widely and can include digestive issues such as bloating, diarrhea, constipation, and abdominal pain. Other common symptoms are headaches, fatigue, joint pain, and skin problems like eczema or rashes. Some people experience neurological symptoms like numbness in the legs, arms, or fingers, as well as cognitive issues like brain fog and difficulty concentrating. Here are some common symptoms ranked.

More from NIH: Celiac disease

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1
Fatigue
179
37
Total Votes: 216
Persistent tiredness and lack of energy, even after adequate sleep. Gluten intolerance can cause inflammation, disrupt sleep, and lead to nutrient deficiencies (like iron and B vitamins), all of which contribute to exhaustion.

2
Weight loss
149
10
Total Votes: 159
In some cases, gluten intolerance can lead to significant weight loss due to malabsorption of nutrients, persistent diarrhea, and a reduced ability to absorb fats, proteins, and carbohydrates.

3
Diarrhea
157
25
Total Votes: 182
Frequent, loose, or watery stools occur when gluten damages the gut lining, leading to malabsorption and irritation in the digestive tract. This can also result in dehydration and electrolyte imbalances.

4
Depression
153
23
Total Votes: 176
Gluten intolerance has been linked to depression due to its effects on the gut-brain axis. Chronic inflammation, poor absorption of mood-regulating nutrients, and disrupted gut bacteria can all contribute to low mood and hopelessness.

5
Anxiety
135
6
Total Votes: 141
The gut and brain are closely connected. Gluten-related inflammation can lead to imbalances in neurotransmitters like GABA and serotonin, increasing feelings of worry, nervousness, and panic.

6
Irritability
162
35
Total Votes: 197
Mood swings and heightened frustration levels are common. Gluten-induced inflammation in the gut can affect neurotransmitter production, particularly serotonin and dopamine, leading to increased irritability.

7
Sinus irritation
146
20
Total Votes: 166
Gluten can trigger nasal congestion, postnasal drip, and sinus inflammation, sometimes mimicking seasonal allergies. This is likely due to an immune system response that increases mucus production.

8
Low appetite
153
27
Total Votes: 180
Ongoing nausea, stomach discomfort, and bloating from gluten intolerance can suppress hunger, making meals less appealing and leading to unintentional weight loss.

9
Gas
154
32
Total Votes: 186
Excessive flatulence and bloating occur due to undigested gluten fermenting in the gut, leading to bacterial overgrowth and excess gas production. This can be particularly pronounced in those with IBS-like symptoms.

10
Flaking scalp
127
9
Total Votes: 136
Persistent dandruff or dry, flaky scalp may be linked to gluten intolerance due to poor nutrient absorption, particularly of zinc, omega-3s, and B vitamins, which are essential for skin and scalp health.

11
Headache
140
36
Total Votes: 176
Recurring headaches and tension headaches are common after gluten consumption. They may be caused by inflammation, dehydration, or histamine intolerance linked to gluten sensitivity.

12
Nausea
110
9
Total Votes: 119
A common symptom of gluten intolerance, nausea can occur shortly after eating gluten or persist for hours due to digestive distress and inflammation. In severe cases, it can lead to vomiting.

13
Swollen throat
110
10
Total Votes: 120
Some individuals experience throat tightness, swelling, or discomfort after eating gluten. This can be caused by immune system activation or mild allergic reactions, leading to inflammation in the throat.

14
Brain fog
129
32
Total Votes: 161
Difficulty focusing, slow thinking, and forgetfulness can occur due to gluten-induced inflammation in the gut, which affects cognitive function. Some individuals report feeling mentally sluggish for hours or days after consuming gluten.

15
Bloating
112
19
Total Votes: 131
Abdominal swelling, discomfort, and tightness after eating gluten occur due to digestive irritation, fermentation of undigested food, and fluid retention in the intestines. This is a hallmark symptom of gluten intolerance.

16
Migraine
112
21
Total Votes: 133
Severe, throbbing headaches, often accompanied by nausea and light sensitivity, can be triggered by gluten exposure. The exact cause is unclear but may involve inflammation, changes in blood flow, or histamine release.

17
Hair loss
65
8
Total Votes: 73
Nutrient malabsorption, particularly of iron, zinc, and biotin, can lead to thinning hair or increased shedding over time. Chronic inflammation from gluten intolerance can also disrupt hair growth cycles.

18
Acne
72
15
Total Votes: 87
Gluten-related inflammation can contribute to persistent breakouts, especially cystic acne around the jawline and cheeks. Poor digestion of gluten may also lead to excess sebum production and clogged pores.

19
Rosacea
63
13
Total Votes: 76
Gluten may trigger or worsen rosacea, a skin condition characterized by facial redness and visible blood vessels. Inflammation and immune system dysregulation are believed to be contributing factors.

20
Insomnia
36
6
Total Votes: 42
Difficulty falling or staying asleep can be linked to gluten intolerance due to inflammation, cortisol imbalances, and digestive discomfort disrupting sleep patterns.

21
Canker sores
37
7
Total Votes: 44
Painful ulcers inside the mouth may develop due to gluten intolerance. This is possibly linked to nutrient deficiencies (such as vitamin B12, folate, and iron) and an overactive immune response.

22
Chronic constipation
31
6
Total Votes: 37
Gluten can slow down digestion in some individuals, leading to hard stools, infrequent bowel movements, and chronic constipation. This is often due to gut inflammation disrupting normal motility.

23
Rash
31
6
Total Votes: 37
Itchy, red, or bumpy rashes may appear on the body as an immune response to gluten exposure. Some people develop dermatitis herpetiformis, a specific skin condition linked to gluten sensitivity.

24
Shortness of breath
33
8
Total Votes: 41
Some people experience mild breathing difficulties or chest tightness after consuming gluten, possibly due to inflammation or histamine release affecting the respiratory system.

25
Fluid retention
30
6
Total Votes: 36
Swelling in the hands, feet, and face can occur due to gluten-induced inflammation, which leads to increased water retention and bloating.

26
Vomiting
29
6
Total Votes: 35
In severe cases, gluten intolerance can cause nausea that progresses to vomiting, especially in individuals with heightened immune responses or celiac disease.

27
Eczema flare up
28
6
Total Votes: 34
Many people with eczema notice worsening skin inflammation, redness, and itching after consuming gluten. This may be due to gluten’s effect on the immune system and gut health.

28
Blood in stool
29
7
Total Votes: 36
Chronic intestinal irritation from gluten consumption may lead to small amounts of bleeding in the stool, particularly in individuals with celiac disease or severe gluten sensitivity.

29
Dark circles under eyes
23
6
Total Votes: 29
Poor absorption of essential nutrients, especially iron, folate, and vitamin B12, can cause dark, hollow under-eyes. Chronic inflammation and poor sleep from gluten sensitivity can worsen this symptom.

30
Stomach pain
11
4
Total Votes: 15
Sharp, cramping, or dull abdominal pain is common after eating gluten. This occurs due to gut irritation, inflammation, and difficulty digesting certain proteins in gluten-containing foods.

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