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Trending lists

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What are long-term health effects of GERD (also for acidity or gastritis)?

Long-term untreated GERD can lead to serious health complications, including esophagitis (inflammation of the esophagus), Barrett’s esophagus (a pre-cancerous condition), and an increased risk of esophageal cancer. Chronic acid exposure can also result in narrowing of the esophagus, known as strictures, which can make swallowing difficult. Persistent GERD may cause respiratory issues such as asthma, chronic cough, or laryngitis. It can also damage tooth enamel and contribute to gum disease. Seeking medical treatment early is crucial for preventing these complications.

More from NIH: GERD and Reflux

See what lists are trending: Trending Lists

1
Peptic Ulcers
89
29
Total Votes: 118

In some cases, GERD can cause peptic ulcers, which are sores in the lining of the esophagus, stomach, or upper intestine. These ulcers can cause significant pain and require treatment.


2
Regurgitation
79
20
Total Votes: 99

Ongoing GERD can cause frequent regurgitation of food or sour liquid, leading to a sour taste in the mouth and discomfort. This can impact daily life and worsen overall quality of life.


3
Increased Risk of Esophageal Cancer
79
21
Total Votes: 100

Barrett’s esophagus, which is linked to GERD, increases the risk of esophageal cancer. While the risk is still low, regular monitoring and early detection are important.


4
Esophageal Strictures
90
34
Total Votes: 124

Repeated exposure to stomach acid can cause scarring in the esophagus, leading to strictures or narrowing. This makes swallowing difficult and may require medical intervention to correct.


5
Weight Loss or Malnutrition
86
40
Total Votes: 126

Chronic GERD may make eating uncomfortable, leading to unintentional weight loss or malnutrition. Difficulty swallowing or fear of triggering symptoms can reduce food intake.


6
Esophageal Bleeding
72
27
Total Votes: 99

Severe cases of GERD can cause erosion of the esophageal lining, leading to bleeding. This may result in blood in vomit or stool and requires immediate medical attention.


7
Chronic Sinus Infections
70
28
Total Votes: 98

GERD can contribute to sinus issues by causing inflammation in the throat and nasal passages. Acid reflux may worsen or trigger chronic sinus infections and post-nasal drip.


8
Difficulty Swallowing (Dysphagia)
65
23
Total Votes: 88

Over time, GERD can make swallowing more difficult, a condition known as dysphagia. This can result from esophageal inflammation, scarring, or narrowing due to acid damage.


9
Psychological Impact
55
15
Total Votes: 70

Living with chronic GERD can take a toll on mental health. The discomfort, pain, and lifestyle changes required to manage the condition may contribute to stress, anxiety, and depression.


10
Voice Changes
43
8
Total Votes: 51

Acid reflux can irritate the vocal cords, leading to changes in your voice. People with GERD may notice persistent hoarseness or a deeper voice over time due to chronic irritation.


11
Barrett’s Esophagus
65
32
Total Votes: 97

Long-term, untreated GERD may cause Barrett’s esophagus, a condition where the lining of the esophagus changes. This can increase the risk of esophageal cancer, though it’s still relatively rare.


12
Respiratory Issues
44
20
Total Votes: 64

In severe cases, GERD can lead to chronic respiratory problems such as bronchitis or pneumonia. This occurs when stomach acid is aspirated into the lungs, causing inflammation and infection.


13
Laryngitis
45
22
Total Votes: 67

Repeated acid exposure can irritate the vocal cords, leading to chronic laryngitis. Symptoms include hoarseness, voice changes, and the sensation of a lump in the throat.


14
Heartburn Medications Side Effects
34
13
Total Votes: 47

Long-term use of GERD medications like proton pump inhibitors (PPIs) can lead to side effects such as nutrient malabsorption (e.g., magnesium and vitamin B12), increased fracture risk, and gut infections.


15
Dental Erosion
24
5
Total Votes: 29

Chronic acid reflux can erode tooth enamel, leading to dental issues like sensitivity, cavities, and decay. This occurs when stomach acid reaches the mouth during reflux episodes.


16
Chronic Cough
26
9
Total Votes: 35

Acid reflux can irritate the throat and airways, leading to a chronic cough. This cough often persists even in the absence of heartburn symptoms and may be mistaken for other conditions.


17
Esophagitis
30
14
Total Votes: 44

GERD can lead to inflammation of the esophagus, known as esophagitis. Over time, stomach acid irritates the esophageal lining, causing discomfort, pain, and difficulty swallowing.


18
Asthma Exacerbation
23
8
Total Votes: 31

GERD can worsen asthma symptoms by irritating the airways with stomach acid. The acid can cause constriction and inflammation in the lungs, leading to breathing difficulties.


19
Sleep Disruptions
28
14
Total Votes: 42

GERD can interfere with sleep, particularly for those who experience nighttime reflux. Acid reflux during sleep may cause frequent waking, discomfort, and poor sleep quality.

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